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This method of use will result in further thyroid damage (5) and weight gain once you stop the medication. Beware of this trap! The traditional advice is to take phentermine daily for several months and then give yourself a holiday. This holiday is supposed to give your body a break and resensitize it to the medication.

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The expected average weight loss with phentermine use is 5% of your initial body weight. Yet, over 12 weeks, it can be as high as 10%. This equates to a weight loss of 10–20 pounds (4.5–9 kg) for a 200 pound (90.7 kg) person. In a meta-analysis of six studies, people who took the average dose of 27.5 mg of phentermine for 13 weeks lost an ...

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